Characteristics of the Corticosteroids

Corticosteroid 

Relative sodium-retaining potency* (mineralocorticoid)

Relative anti-inflammatory potency* (glucocorticoid)

Approximately equivalent IV or oral doses

Approximate plasma half-life (hours)

Biological half-life (hours)

*Hydrocortisone

1

1

20 mg

1-2

8-12

Betamethasone

0

25

0.75 mg

3-5

36-54

Cortisone

0.8

0.8

25 mg

0.5-1.5

8-12

Dexamethasone

0

25

0.75 mg

3-4.5

36-54

Fludrocortisone ("Florinef")

125

10

 

3.5

18-36

Methylprednisolone ("Medrol")

0.5

5

4 mg

3.5

18-36

Prednisolone

0.8

4

5 mg

2.1-3.5

18-36

Prednisone

0.8

4

5 mg

3.4-3.8

18-36

Triamcinolone

0

5

4 mg

2-5

18-36